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PMID: 30580599. DOI: 10.1080/14786419.2018.1536134. Abstract. The hypolipidemic effect of 10-DHGD was previously reported owing to its anti-inflammatory and anti-oxidant properties. We further investigated the anti-inflammatory role of 10-DHGD in modulating atherogenicity by targeting proproteinconvertasesubtilisinkexin-9 (PCSK-9).
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The official website of A. Lange & Söhne offers information about all timepieces and their families as well as exciting insights into the world of precision watchmaking.When they developed the ZEITWERK, Lange’s engineers questioned .We would like to show you a description here but the site won’t allow us.The LANGE 1 symbolises the rebirth of our manufacture and also laid the .
The LANGE 1 symbolises the rebirth of our manufacture and also laid the .
A. Lange & Söhne’s master watchmakers are regularly confronted with design .The design language reflects the one-of-a-kind character of the watch, undeniably .Since A. Lange & Söhne was re-established in 1990, Walter Lange's proclaimed goal .Following the relaunch of the brand, A. Lange & Söhne presented their first .
Lange watches are manufactured in Glashütte, Germany. Our company was .
A. Lange & Söhne | Select your Country/Region. Skip to main content. Experience our limited-edition anniversary debuts, celebrating 30 years of LANGE 1 in our U.S. boutiques. .Lange & Söhne unveiled the timepiece in 2013, and with a price tag of over 2 million USD, it is one of the most expensive watches in the world. It takes an entire year to produce a single .50°51′05″N 13°46′52″E / 50.851498°N 13.781242°E A. Lange & Söhne is a trademark of Lange Uhren GmbH, a German manufacturer of luxury and prestige watches. The company was originally founded by Ferdinand Adolph Lange in Glashütte, Kingdom of Saxony in 1845. The original A. Lange & Söhne was nationalized and ceased to exist in 1948, following the occ.
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LANGE 1. Distinctive. In every detail. With its one-of-a-kind design, sophisticated manufacture movement and artisanal finish, the LANGE 1 epitomises the essence of the A. Lange & Söhne . The Lange 1 by A. Lange & Söhne put the Swiss watch industry on notice in 1994. This is the complete history of the most famous watch from Germany. For the iconic A. Lange & Söhne Lange 1, you’re looking at least ,300, while the Grand Lange 1 Moon Phase or Lange 1 Time Zone are much more expensive at ,600 or ,800 respectively. A. A. Lange & Söhne .The Grand Lange 1 Lumen stands out in the A. Lange & Söhne collection as the first Lange watch to feature a luminescent oversized date. It also has a semi-transparent dial and luminescent .
At A. Lange & Söhne, Handwerkskunst, the German word for “artisanship”, is an attribute of distinction that we have been using since 2011 to identify special limited-edition watches .
Today, we’ll revisit the A. Lange & Sôhne Lange 1 by bringing you an in-depth and as exhaustive as possible guide looking at all models, all complications, all references, and illustrated by a movie featuring the brand’s CEO.La LANGE 1 est inimitable. Avec sa grande date signature et son cadran asymétrique à l'équilibre parfait, elle a su tracer sa propre voie. Le mouvement de manufacture de la LANGE 1 dévoile de nombreuses particularités de l'art horloger allemand, comme la platine trois-quarts en maillechort naturel, le coq de balancier gravé à la main, les chatons en or vissés et la finition minutieuse .
Some A. Lange & Söhne watches combine several great complications and sophisticated technical solutions in one single watch. Read more. Manufacture movements. Every A. Lange & Söhne timepiece is equipped with a manufacture movement. To be more precise: all calibres are developed, crafted, finished and assembled in our manufacture in Glashütte.In the LANGE 1, it can be found in two places: the ratio between the diameter of the dial and that of the hour and minute circle is in keeping with this principle as are the proportions of the date aperture. The displays are laid out in the form of an isosceles triangle. Its imaginary vertical baseline connects the centre of the outsize date .In the LANGE 1, it can be found in two places: the ratio between the diameter of the dial and that of the hour and minute circle is in keeping with this principle as are the proportions of the date aperture. The displays are laid out in the form of an isosceles triangle. Its imaginary vertical baseline connects the centre of the outsize date .Chaque garde-temps A. Lange & Söhne renferme un mouvement de manufacture. Plus exactement, tous nos calibres sont développés, fabriqués, finis et assemblés au sein de notre manufacture de Glashütte. Cette approche est unique. Grâce à elle, nous avons toute latitude pour donner vie à nos idées créatives et faire avancer l'horlogerie .
A. Lange & Söhne's current range includes three versions of the three-hand Odysseus: ref. 363.179 in stainless steel, ref. 363.068 in white gold, and ref. 363.117 in titanium (limited to 250 pieces).All three watches measure 40.5 mm in diameter and 11.1 mm in height. Each timepiece is powered by the automatic in-house caliber L155.1 with a 50-hour power reserve.The LANGE 1 symbolises the rebirth of our manufacture and also laid the foundation for a unique design language. The configuration of its off-centre and asymmetrical dial constitutes a milestone in the world of precision watchmaking. Further creations followed that have not only become our very own classics ‒ they are also considered classics .
Some A. Lange & Söhne watches combine several great complications and sophisticated technical solutions in one single watch. Read more. Manufacture movements. Every A. Lange & Söhne timepiece is equipped with a manufacture movement. To be more precise: all calibres are developed, crafted, finished and assembled in our manufacture in Glashütte. This year is a big one for A. Lange & Söhne. It's the 30th anniversary of the brand and 25th anniversary of the Datograph. While I'm sure the brand has more in store this year, the Datograph is getting its moment today, thanks in part to the introduction of the new Datograph Perpetual Tourbillon Lumen in Honeygold, a watch that combines two of the most important . The opinion of this individual collector – who, it's worth noting, has owned multiple A. Lange & Söhne watches over the years – was that the Odysseus was about 95 percent of the way to becoming a classic. It was an enviable position to be sure, but it also wasn't the surefire hit that A. Lange & Söhne had hoped for. A. Lange & Söhne released its first self-winding watch, the Langematik, three years after it launched the Lange 1. To increase the movement’s winding efficiency, the solid gold rotor in the Langematik is equipped with an outer platinum segment.
Lange also kept the case design language intact while adding the chronograph function. On its face it's an easy feat; the original Odysseus came with pushers above and below the crown already so it seems obvious to put a chronograph in the case and call it a day. But those pushers changed the day and date, so they required their own solution.别具一格的设计风格，一览无余的精密细节。 致敬 lange 1 朗格 1 系列问世 30 周年。lange 1憑藉別具一格的設計、精密的機械裝置和精湛修飾技藝，盡顯朗格精髓所在。 跳至主內容 你目前正在瀏覽的網站是 中國香港特別行政區 版本。 A Genuine Lange Watch with an Expanded Field Of Application The rate values are equally impressive. The Odysseus that we tested gained only 1 second per day on the wrist. Our timing machine reconfirmed the accurate .
Lange's CEO, Wilhelm Schmid, says, "Few people know that the conceptualization of the Datograph started with the dial. The idea to arrange the outsize date and the two sub-dials in a way that they form an equilateral . The purest form of the Lange 1, the classic hand-wound 38.5mm model The basics of the Lange 1. While the Lange 1 is regarded by most as the quintessential A. Lange & Söhne, a watch that in 2022 is almost identical (visually at least) to the model introduced in 1994, it .
Ferdinand Adolph Lange, son of Johann Samuel Lange, was born in Dresden on 25 February 1815. When his parents were separated, he was adopted by a foster family, who luckily offered him a chance of proper education. [16] In 1829, he entered the Technische Bildungsanstalt (technical education institute) of Dresden. [17] The training in the school was accompanied by .The DATOGRAPH was the first A. Lange & Söhne chronograph developed and crafted in our manufacture after the re-establishment. With its singular combination of a sophisticated manufacture calibre and well-organised dial, it is still today a benchmark in the art of short-time measurement, and a symbol of the innovative powers of the manufacture.Typical Lange quality hallmarks such as bridges made of untreated German silver, chamfered and polished edges, gold chatons and blued screws can be admired through the sapphire-crystal caseback. Explore further Watches and Wonders 2024. Discover the A. Lange & Söhne Watches and Wonders 2024 novelties: the DATOGRAPH UP/DOWN and the DATOGRAPH .The LANGE 1 symbolises the rebirth of our manufacture and also laid the foundation for a unique design language. The configuration of its off-centre and asymmetrical dial constitutes a milestone in the world of precision watchmaking. Further creations followed that have not only become our very own classics ‒ they are also considered classics .
In line with Ferdinand Adolph Lange’s character, the dial design is subtle yet rich in detail. The no doubt most prominent feature of the 1815 is the railway-track minute scale. The watch thus builds a bridge into the era of nascent rail travel, at a time when pocket watches became ever more important, and when Ferdinand Adolph Lange founded .
Experience our limited-edition anniversary debuts, celebrating 30 years of LANGE 1 in our U.S. boutiques. DISCOVER MORE. Choose your country or region. Choose your country or region Asia Back 中国 (ZH-HANS) Hong Kong SAR, China (EN) 中国香港特别行政区 (ZH-HANS) .In line with Ferdinand Adolph Lange’s character, the dial design is subtle yet rich in detail. The no doubt most prominent feature of the 1815 is the railway-track minute scale. The watch thus builds a bridge into the era of nascent rail travel, at a time when pocket watches became ever more important, and when Ferdinand Adolph Lange founded .A. Lange & Söhne’s master watchmakers are regularly confronted with design challenges when they develop new movements. Frequently, the outcome is totally new and innovative approaches such as the world’s first triple rattrapante mechanism. What is equally important is the emphasis on optimising proven, existing solutions.Hier finden Sie einen Überblick über alle Zeitmesser von A. Lange & Söhne: Farbvarianten, Produktinformationen und technische Details.
Les nouvelles versions de la LANGE 1 rayonnent d'une élégance festive, comme il se doit pour un anniversaire. La montre en platine 950 possède un cadran recouvert d'onyx. Rarement utilisée en haute horlogerie, cette pierre précieuse séduit par son éclat noir de jais : c'est la première fois qu'elle orne un modèle de la famille LANGE 1.
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